Different microreactors are available at our research group. We use both complete systems and self-made systems by combining one or more pumps with a tubular reactor and/or a microchip. Within our lab, flow reactions with O2, CO2, H2, and CHF3 are possible. In-line work can be done by a Zaiput liquid/liquid separator and in-line analysis by an in-line FTIR (Bruker).
Complete systems
Labtrix® Start (Chemtrix) Internal volume: 1, 5 or 10 µl depending on the reactor chip used Temperature range: -15°C to 195°C Pressures up to 25 bar Wetted materials: glass, PEEK, PTFE, Techtron
KiloFlow® (Chemtrix) Internal volume: 13 ml Temperature range: 10°C to 150°C Pressures up to 20 bar Wetted materials: glass, PEEK, ETFE, perfluoroelastomer
X-CubeTM (ThalesNano) Temperature range: 20°C to 200°C Pressures up to 150 bar Wetted material: stainless steel Compatible with gases (H2, O2, ...) Compatible with catalyst cartridges (Pd/C, Raney Ni, ...)
H Cube Mini (ThalesNano) Temperature range: 20°C to 100°C Pressure 1 bar to 100 bar Flow rate 0.3-3 ml/min Maximum hydrogen production rate 25-30 Nml/min Water reservoir capacity 100 ml
CPC® College System 2 ml microreactor (stainless steel) + 45 ml residence time unit
Vapourtec Easy-MedChem V3 An adjustable packed bed column reactor – ambient to 150°C A tube reactor assembly – ambient to 150°C User interface with manual control software 3 V-3 pumps
Africa (Syrris) Fully automated, flexible and easy-to-use microreactor system Wide temperature range Reagent pump module with flow rate range of 2.5-2500 µl/min
Pumps
ReaXus-Model 6010R (Teledyne ISCO) High performance reciprocating peristaltic pump Accurate flow rate control up to 10 ml/min Pressure capability up to 6000 psi (414 bar)
WADose (Flusys) Compact high-pressure dosing peristaltic pump (dual piston) Dosing range 0.001-40 ml/min Viscosity range up to 40 mPa.s Pressure range atm-400 barg Pump head material PEEK
FlowSyn Binary Pump Module (Uniqsis) Peristaltic pump Flow rates from 5 µl/min up to 10 ml/min Glass static mixer + Teflon 5 ml coil reactor 10 bar BPR
Intelligent Pump AI-12 (Flom) Peristaltic pump Double-plunger reciprocating method Maximum discharge pressure 5MPa Range of flow rate setting 0.1-50 ml/min Pressure limiter upper limit 0-10 MPa
Glass chips: e.g. Glass static reactor 1.6 mL (Uniqsis)
PTFE tubing with multiple radii
PFA tubing with multiple radii
PEEK tubing with multiple radii
Bruker Avance-III 400 MHz NMR Spectrometer equipped with BRUKER 5 mm BBFO 400 MHz Z-gradient high resolution probe
Description
State-of-the-art NMR spectrometer equipped with an observe broadband high resolution probe, fitted with an actively shielded single axis Z-gradient for 5 mm sample diameters and 400 MHz standard-bore or wide-bore magnets. The inner NMR coil can be tuned to observe 19F or any nucleus in the range from 31P to 15N. The outer NMR coil is tuned for either 1H decoupling or observation. The probe is fitted with a 2H lock channel and automatic tuning and matching (ATM).
Signal/Noise
19F sensitivity ≥250:1 (TFT sample, with 1H decoupling)
